Reactive oxygen species (ROS) are part of the body’s antimicrobial response and have a major role in wound healing. Members of the ROS family include O2- , O2-2, H2O2. The term Reactive Oxygen® refers to the antimicrobial mechanism for SurgihoneyRO™. SurgihoneyRO™ is an antimicrobial wound gel that delivers precisely controlled and sustained, therapeutic levels of Reactive Oxygen® to the wound bed. SurgihoneyRO™ has been shown to have fast-acting antimicrobial action, and the ability to prevent biofilm formation, eradicate mature biofilm and kill almost all of the 12 multi-drug resistant bacteria listed in a World Health Organization (2017) report, including all those commonly found in chronic wounds.