There is growing concern regarding antibiotic resistance, and it is estimated that if no action is taken, antimicrobial drug-resistant diseases could cause 10 million deaths each year by 2050, costing £66 trillion (Interagency Coordinating Group on Antimicrobial Resistance, 2019). As such, clinical studies focused on honey as an antimicrobial are emerging. Honey is a natural and effective therapy with broad-spectrum antimicrobial activity and no risk of resistance, which may potentially reduce use of antibiotics (Yaghoobi et al, 2013). This Made Easy explores the role of natural wound healing remedies, the impact of Medical Grade Honey (MGH) and the range of L-Mesitran® (H&R Healthcare) products.