Journal Articles

Using PHMB antimicrobial to prevent wound infection

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Using PHMB antimicrobial to prevent wound infection

David Gray, Keith Moore
31 May 2007

Post-operative wound infections may result in delayed healing, extended hospital stay and increased costs. The increase in antibiotic-resistant bacteria mitigates against the prophylactic use of antibiotics. An effective alternative is the use of antiseptics that are less likely to generate resistance. AMD™ wound dressings use polyhexamethylene biguanide (PHMB) which has a low toxicity for wound cells and is effective in killing antibiotic-resistant bacteria. This paper reviews the evidence for the efficacy and cost-effectiveness of AMD dressings in the prevention of surgical site infections when routinely used in standard wound care protocols.

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