Expert panel report: The role of topical oxygen therapy in the management of diabetic foot ulcers

Share this article

Expert panel report: The role of topical oxygen therapy in the management of diabetic foot ulcers

Duncan Stang, Luxmi Dhoonmoon, Martin Fox, Mike Edmonds, Paul Chadwick, Richard Leigh, Stella Vig
18 June 2019

This document covers the role, current evidence and practicalities of topical oxygen therapy (TOT) in diabetic foot care in the UK. Diabetic foot ulcers (DFUs) are complex chronic wounds that have a major long-term impact on the morbidity, mortality and quality of patients’ lives (Wounds International, 2013).

TOT in wound care has been understood to aid wound healing since the 1960s and has been shown to be especially beneficial for DFUs where there is an ischaemic or a hypoxic element. An Expert Panel gathered in London in early 2019 to discuss the position and appropriate use of TOT in the UK today.

Burden of DFUs 
Diabetic foot disease is just one complication of diabetes mellitus, which can lead to non-healing wounds and amputations if left unmanaged. Unlike other chronic wounds, DFUs are often complicated by other wide-ranging diabetic and metabolic changes, such as neuropathy and vascular disease (Wounds International, 2013), which can make them particularly difficult to manage and heal.

Each year, an estimated 2–2.5% of people with diabetes develop a DFU (Diabetes UK, 2017). In the Burden of Wounds study, it has been estimated that there were 169 000 DFUs across the UK, equating to 5% of adults with diabetes (Guest et al, 2015).

Diabetic foot disease is the largest single reason for hospital admissions among people with diabetes (Boulton et al, 2005). The NHS cost of DFUs is estimated at £1 billion per year (Kerr, 2017; Guest et al, 2018), but this does not include the additional social costs to the patient, such as reduced mobility and sickness absence, which are estimated at £13.9 billion per year. The indirect, intangible costs to the person with diabetic foot disease are also high, with many experiencing a poorer quality of life than those without foot disease (Vileikyte, 2001). Individuals who develop a DFU are also at greater risk of premature death, myocardial infarction and fatal stroke than those without a history of diabetic foot ulceration (Brownrigg et al, 2012).

Free for all healthcare professionals

Sign up to the Wounds Group journals

By clicking ‘Subscribe’, you are agreeing that the Wounds Group are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our privacy policy.

Are you a healthcare professional? This website is for healthcare professionals only. To continue, please confirm that you are a healthcare professional below.

We use cookies responsibly to ensure that we give you the best experience on our website. If you continue without changing your browser settings, we’ll assume that you are happy to receive all cookies on this website. Read about how we use cookies.

I am not a healthcare professional.