Surgical wounds generally heal by primary intention with no significant problems. However, the development of blisters can be painful, extend the inpatient stay, be expensive and may lead to surgical site infection. Numerous studies have compared a variety of wound dressings, evaluating their performance in preventing the development of wound blistering to perioperative wound skin, yet none present conclusive recommendations. A wound dressing should maintain a warm, moist healing environment and should not damage the periwound area, which could lead to blister formation. Protection of the periwound area is vital and can be achieved by choosing a dressing that does not adhere to surrounding skin, is easy to apply, easy to remove and flexible.