Infection is an important and common complication in wound care and can develop in any wound type. Clinicians involved in wound care need to be able to accurately assess and identify symptoms of wound infection. Early intervention should be carried out according to evidence-based best practice within a structured framework to standardise care (Wounds UK, 2021). This Made Easy will introduce the Therapeutic Index for Local Infections (TILI) score, a diagnostic tool designed to facilitate identification and decision-making around infection for staff of all levels (Dissemond et al, 2020a).