This article describes two case reports using an innovative approach to the prevention and management of infection in diabetic foot wounds. In both case reports, Cutimed® Sorbact® (BSN medical) was successfully used to help prevent wound re-infection and enable the wounds to move on to complete healing. The dressings work on the principle of hydrophobicity, offering an alternative to the use of established antimicrobial products. Both wounds had a history of osteomyelitis and soft tissue infection in patients with predominantly neuropathic feet. These cases are part of an ongoing formal product evaluation which will be published later in the year.