This article is based on a symposium held at the Wounds UK conference in Harrogate on 10 November 2015. The symposium opened with two distinct aims: first, to look at what we can see, specifically in terms of pressure ulcer categorisation, and discuss initiatives that have improved confidence in diagnosis and care. Second, to explore what we cannot see, with a focus on biofilm management, reviewing emerging strategies aimed at combatting this invisible threat.