This series of five case studies focuses on patients with nonhealing venous leg ulcers who were treated with CelluDress-PHMB (Medicareplus International), a sterile, moist wound dressing impregnated with a polyhexamethylene biguanide (PHMB) Antimicrobial Complex. In addition to chronic and lower leg wounds such as venous leg ulcers, the dressing is indicated for use in postoperative, superficial and deep wounds, first and second-degree burns, diabetic foot ulcers and pressure ulcers (category I and II) at risk of infection, with low to moderate exudate.