The COVID-19 pandemic has highlighted areas of skin damage that have previously been written about in the tissue viability literature, but are not necessarily seen as mainstream topics. This article will discuss some of these topics, to include: personal protective equipment (PPE) skin damage to healthcare staff; vasopressor therapy skin damage; and acro-ischaemia or ‘Covid toes’. Prevention strategies for PPE related skin damage will be briefly discussed. Plus look at how vasopressor skin damage can be mistaken for a deep tissue injury (DTI), and cover what to look for to differentiate between the two. Finishing with how acro-ischaemia may also be mistakenly categorised as a DTI.