While there are several definitions of chronic or nonhealing wounds – and it is generally accepted that under normal circumstances, wound healing occurs within 6 weeks of injury and wounds that fall outside that are generally referred to as chronic wounds – the same cannot be said for burn wounds. We know that a superficial burn will heal in 5–7 days and a superficial dermal burn within 7–10 days, but little is understood about the normal healing trajectory of deep dermal or full-thickness burns.