Oxygen has a crucial role in wound healing; 97% of chronic, non-healing wounds have been shown to have low oxygen levels (Hauser, 1987). Topical oxygen therapy has been shown to be effective in treating non-healing wounds, but is still underutilised. A working group of key opinion leaders met in February 2015 to determine the potential role of topical haemoglobin in non-healing wounds and to develop a clear decision-making pathway for clinical practice, as well as sharing practical tips for use. The group’s consensus recommendations on appropriate use are presented here.