Zinc is the second most abundant trace metal in the human body and is present in all living cells and body secretions. Topical zinc has been used for over 3,000 years in the treatment of skin conditions and wounds (Lansdown et al, 2007). It is reported as having a number of beneficial effects on wound healing, including antiseptic, astringent, anti-inflammatory and anti-microbial (Maher, 2015). This article will discuss the benefits of topical zinc in the management of venous eczema and ulceration and explore the use of Andoflex UBZ in the management of venous disease.