Epidermolysis bullosa (EB) is the term given to a large group of genetically determined skin disorders in which the common factor is fragility of the skin and mucous membranes (Lin and Carter, 1992). There is a wide range of severity, varying between mild discomfort and death in early infancy. The presence of multiple wounds of varying gestation make management difficult and care must be regularly modified. Non-cutaneous complications further compromise well-being. The aim of this paper is to discuss the practice of bathing for severely affected infants and children and whether this is always appropriate.