Pressure ulcers place a significant burden on both patients and the healthcare system and it has been suggested that the use of negative pressure wound therapy (NPWT) in the treatment of pressure ulcersmay lead to faster healing.However,the role ofNPWT in the management of chronic wounds has become a controversial issue, following a Cochrane review that concluded there was no valid or reliable evidence to suggest NPWT aided chronic wound healing (Ubbink et al, 2008). The aim of this article is to discuss the evidence assessed in the Cochrane review, as well as to consider other types of evidence available and more recent studies. Current evidence does not allow a firm conclusion regarding the efficacy of NPWT for the management of pressure ulcers, but is suggestive of improvements in ulcer size and wound bed quality.