Lack of knowledge of the processes related to wound healing currently prevents us from describing in detail those processes in a patient, organ, tissue or cell that are causing the wound or delaying its healing (Franz et al, 2000; Gottrup et al, 2010). Some authors, indeed, do not believe current knowledge allows for evidence-based medicine in wound care (Helberg et al, 2006; Karavan et al, 2015). This article presents a framework that may help to support the diagnosis, improve communication between professionals and allow for information exchange with other medical fields.