Designing a questionnaire for effective quantitative data analysis in wound care requires careful thought. We are usually trying to ‘measure the unmeasurable’ i.e. capture one or more constructs for which no objective measure exists. Hence, we need to ensure that the items we include to measure those constructs, which can elicit either numerical or categorical responses, adequately capture the essence of the constructs without duplication, omission of some important aspect of the construct or inclusion of irrelevant items. We need a scoring system that is easy to manage and results in meaningful measures. If inferential analysis is to be conducted from our questionnaire data, this needs particular thought: for example, we may need to collect demographic or job-related information recorded in suitable categories to facilitate comparative analysis of construct scores. Pragmatically, we should also be concerned with the length of the questionnaire, the clarity of the items, be clear what is the unit of analysis, who the questionnaire is designed for and the population to which any generalisation is to be made.