Negative pressure wound therapy (NPWT) has been traditionally associated with large, open chronic and acute wounds. As technology has progressed, these systems have become smaller, portable and more useful in other indications. The use of NPWT in closed incisions has been pioneered in orthopaedic wounds, however, more recently, incisional NPWT has been used in Caesarean (C)-section patients to help reduce the risk of surgical site infection (SSI) in individuals with a high body mass index. This article discusses the possible modes of action of NPWT for incisional wounds, and the impact of using such a device in an NHS Trust to help reduce the risk of SSI in C-section patients.