This document has been compiled to fulfill a distinct need. The literature on the management of wound infection has been criticised for its paucity of reliable evidence.

This, we believe, is because there are Cochrane-style systematic reviews drawing attention to the lack of evidence-based use for topical antiseptics from selected randomised, controlled trials (RCTs). Nevertheless, clinical practice needs persist and patients require treatment. Consequently, this exercise has been undertaken and this second edition is intended to address apparent shortcomings, and so fill the gap.

In the UK, the repercussions from these systematic reviews have led to restrictions in the availability of topical antimicrobial dressings, notably those containing silver (White, 2010a). These restrictions have provoked considerable and widespread concern among clinicians, as they are not necessarily to the benefit of the patient, nor do they help clarify any alternative best practice.